1. Discovery Science  -  'Blue-sky' research to discover new mechanisms driving poor mental health which could be the focus of future treatments. We think the body could be one important, neglected source of information about mental health, including the sense of the internal condition of the body (see our paper in The American Journal of Psychiatry ), circadian rhythm (see our new paper in eLife), and metabolism (see this preprint). 

2. Experimental Medicine  -  Experiments to test the causal role of potential mechanisms (i.e. does something merely correlate with worse mental health, or does it actually cause worse mental health - meaning it could be a treatment target?). To do this, we use methods like pharmacology to manipulate chemicals in the brain or body (by targeting the stomach with a a drug, our study in Current Biology discovered that the state of the gut is one cause of disgust avoidance), brain stimulation to change brain activity, and psychological interventions to modulate cognitive targets (e.g., we showed that a common psychological therapy technique changes learning from negative outcomes in this study in Psychological Medicine).

3. Translational Neuroscience  - Clinical trials to test new, neuroscience-based interventions. We are especially excited about 'acute augmentations' of psychological therapy, or ways that neuroscience can be used to boost the efficacy of psychological therapy (see this clinical trial combing brain stimulation and psychological therapy in Neuropsychopharmacology, and our analysis in Nature Mental Health.